Advances in diagnostic tests for bacterial STDs

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Advances in diagnostic tests for bacterial STDs.

Because of their asymptomatic nature and nonspecific symptoms, laboratory tests are often required to diagnose a sexually transmitted infection. Over the past few years, there have been advances in technology, such as the development of nucleic acid amplification assays, which have improved our ability to diagnose infections caused by Chlamydia trachomatis. The finding that nucleic acid amplifi...

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CpG DNA analysis of bacterial STDs

BACKGROUND Bacterial infections in the genital tract frequently result in morbidity through a variety of inflammation based symptoms. One component of the bacteria that may trigger host inflammatory response is their DNA. CpG motifs in this DNA are known targets for Toll-like receptor 9 (TLR9), which is a pathogen-recognition receptors focusing on CpG DNA. The activation of TLR9 induces the NF-...

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Rapid point of care diagnostic tests for viral and bacterial respiratory tract infections--needs, advances, and future prospects.

Respiratory tract infections rank second as causes of adult and paediatric morbidity and mortality worldwide. Respiratory tract infections are caused by many different bacteria (including mycobacteria) and viruses, and rapid detection of pathogens in individual cases is crucial in achieving the best clinical management, public health surveillance, and control outcomes. Further challenges in imp...

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Diagnostic tests for chancroid.

Background The identification of the causative agent of chancroid, Haemophilus ducreyi, was first reported in 1889 by August Ducrey, as a short streptobacillary rod with rounded ends, following experiments in which he autoinoculated patients’ forearms with pus from their genital ulcers. Bezancon et al subsequently inoculated the forearms of human volunteers with culture purified organisms and p...

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Diagnostic tests for frailty

A common way of allowing heterogeneity between individuals in models for lifetime data is to introduce an unobservable individual random effect Z. In a proportional hazards framework, the individual’s hazard becomes zhb(t) where hb(t) is the baseline hazard. The random variable Z is often assumed to follow the Gamma or Inverse Gaussian distribution. We develop here diagnostic tests for these as...

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ژورنال

عنوان ژورنال: Salud Pública de México

سال: 2003

ISSN: 0036-3634

DOI: 10.1590/s0036-36342003001100017